Jagor moko mi France uketho dhanu ung'eyo rac pa sindhani ma bith i ot yath ingey ret ma rac ma ukelo pii ma wok kud i solvent. Kawoni elwongo pi yubu jam loko sindhani pi loko solvents nyo reagents pi medo ber pa laboratory. 1
I Dwi mir Abusiel 2018, nyathin musomo ma oro pare 22 Nicolas ubedu katiyo i ot yath pa Sebastien Vidal i University of Lyon 1. Epodho syringe pa dichloromethane (DXM) i flask man epodho cinge. Vidal ukwanu nia pii ario nyo ma piny pa 100 microliters pa DXM udong i sindhani man umondo i cing.
Cal mapol nyuthu ango ma utime i ngeye – lembe ma jugoro i gazeti uketho dhanu moko copo nwangu cal (piny) ma nyayu lworo. Ikind dakika 15 ingey juku cinge, Nicolas unwangu rangi macol iwi cinge. I ngei sawa ario, ngete pa rangi macol ucaku doko col, ma nyutho acaki pa necrosis – tho pa cell. I kare eni, Nicholas ugam ukwayu nia cinge ubedu malyeth man ecopo tingo gi ngo.
Nicholas umitu jutim ire opareson pio pio pi laru cinge. Daktari, ma ugam uparu niya jubi thume, gi goyo adila ma tho i ngete ma ju goyo ku pala man gi dwoko cinge kendu ku adila ma juwodho kud i cing Nicholas. Daktari ne upoi i ngeye nia ikind oro 25 ma etiyo i ot yath, eneno ngo ret ma kumeno.
Lwic pa Nicholas dong udok kakare, kadi nang goyo gita pare unwangu two necrosis ma unyotho ler pare, ma uketho tego pare man ryeko pare doko nok.
DCM ubedo acel ikin piny ma jutiyo kudu lee i ot yath mi chemistry. DCM Injury Information man Material Safety Data Sheet (MSDS) mio lembe ikum neno wang, neno adila, madhu man yweyo, ento ungo ikum yath, Vidal uwacu. I kare mi lubo tok lembe, Vidal unwangu niya lembe marom utime i Thailand, kadi nang jal ne ungolo ku 2 milliliters pa dichloromethane, adwogi ne jukoro i ot yat mi Bangkok. 2
Lembe eni nyutho nia waraga pa MSDS umaku julok ni medo lembe ikum parenterals, Vidal uwacu. "Ento jadwong para mi gwoko kuc i univasite uwacu ira niya loko waraga mi MSDS bi tero kare malac man bi mito lembe madwong ma jubi coko." Eni uketho i iye somo ikum lei pi nyuthu ret, nyang ikum ret pa kum, man pimo pa daktari.
Lwic pa awiya kwan i rwom matung tung ingey timo yath ma nok pa methylene chloride. Nicaku cing cing ni cing cing cing, dakika 10-15 ingey ret, ingeye sawa 2, sawa 24 (ingeye yath), nindu 2, nindu 5, man oro 1 (cal zo piny)
Ni lubre ku lembe mapol ikum tic pa DCM, Vidal ogeno nia lembe eni jubi nyai iwi ngom zoo. Lembe ma judwoko utiye maber. Ewecu niya waraga ne [jupoko iwi ngom madwong]. "Judong tic mi gwoko kuc kud i yunivasiti mi Canada, US man France giwacu ira niya gibeci ketho lembe eni i yub migi mi somo. Dhanu gifoyowa pi poko lembe eni. Dhanu mapol gimito ngo giwec ikume pi lworo mi nyayu lembe marac [pi kabedo migi] Ento kabedo mwa ubedo ku kony madit nicaku i acaki man podi gibekonyo.
Vidal de mitu ju ma gisomo lembe mi ngec man ju ma gi kelo yath ni yubu cik ma ber man jam tic mange pi tic ma kubang ceng calu tero yath. Paru acel utiye ni tiyo ku sindhani ma "flat-pointed" mi gwoko ret ma jukubo. "Gitiye kawoni, ento pol kare watiyo ku sindhani ma lac i organic chemistry pi en umitu waketh solvents nikadhu kud i rubber stoppers pi gwoko reaction vessels mwa kud i yamo/pii ma woko. "Flat" needles copo kadhu ngo kud i rubber stoppers. Eni epe penji ma yot, ento nyalo bedo ni turo eni bi kelo paru maber.
Alain Martin, jadit mi yot kum man bedo ber i University of Strathclyde's Department of Chemistry, uwaco ni eneno ngo ret ma kumeno. "I ot yath, jubed jutiyo ku syringes ku sindhani, ento ka bedo ber piretek, tic ku micropipettes copo bedu yore maber," emedu, nimakere ku ponji, calu yero tip man tic ku pipettes maber. "Be juponjo awiya kwan mwa kite mi tiyo ku sindhani maber, kite mi ketho man kwanyu sindhani?" epenju. “Ngati moku paru nya ango mange ma jucopo tiyo kudu? Nyo epe.
2 K. Sanprasert, T. Thangtrongchitr man N. Krairojananan, Asia. Pango. J. Med. Toxicology, 2018, 7, 84 (DOI: 10.22038/apjmt.2018.11981)
$210 million ma jumiyo kud i Moderna jalonyo man jalonyo Tim Springer pi konyo sayusac ma ubetimere
Dikiri pa X-ray diffraction experiments man simulations nyutho nia ler ma tek pa laser copo loko polystyrene.
© Royal Society of Chemistry document.write(new Date().getFullYear()); Namba mi goyo nying: 207890