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Nyo pima yot pa lac copo nyutho two Alzheimer's ma podi ucaku con, man ecopo yabo yo pi yub mi pima dhanu mapol? Lembe manyen mi Frontiers in Aging Neuroscience nyutho lembe eni. Ju ma timo sayusac gi temo dul madit pa ju ma twoyo pa Alzheimer ma pek migi tung tung man dhanu ma kumgi yot ma gibedo ku paru maber pi ni nyang tung tung pa biomarkers mi lac.
Ginwangu niya formic acid i lac ubedo lanyuth ma pire tek mi rwinyo pa wic man ecopu bedu lanyuth pa acaki pa two Alzheimer. Yore macon mi ngiyo two Alzheimer utiye tek, yot ungo, man epe ku yore mi ngiyo two. Eni nyutho nia pol pa jurutwo jubedu ka nwango two ne kende kende kani kare ukadhu pi yath maber. Ento, yath ma nyayu remo ungo, ma wel pare yot ungo, man ma yot pi nwangu formic acid copo bedu piny ma daktari penjo pi nyang ikum dhanu con.
"Two pa Alzheimer ubedo two ma rii pi kare malac man ma rii pi kare malac, ma nyutho nya ecopu dongo man rii pi oro madwong mapodi peko mi wic unen ungo," ju goro gi uwacu. "Kit ma two ne caku kudu wok mapodi kare pa two wic ma rwinyo ngo, ma en e dirisa maber pi kony man yath. Pieno, timo sayusac madit pi two Alzheimer i acaki pa dhanu ma oro migi cidho malu piretek."
Dong, ka kony ma jutimo con piretek, pirango ngo wabed ku yub mi ngiyo two pa Alzheimer ma podi ucaku con? Peko utiye i yore ma daktari tiyo kudu kawoni. Maeni uketho i iye positron emission tomography pa wic, ma wel pare tek man eketho jurutwo bedo i radiation. Man de tiye pima ma copo nyutho Alzheimer's, ento mitu remo ma nyai nyo lumbar punctures pi nwangu pii mi wic, ma jurutwo copo bedu ka weko.
Ento, pima lac epe ku remo man yot, ma weko gibedo ber pi pima dhanu madwong. Kadi bende ju ma timo sayusac udaru nwangu lanyuth pa lac pa two Alzheimer, acel de epe maber pi nwangu acaki pa two ne, ma nyutho nya yore maber mi nwangu yath con podi ubedu tek.
Ju ma timo sayusac ma timo sayusac manyen eni gilar gisomo ikum piny moko ma julwongo ni formaldehyde calu lanyuth pa two Alzheimer. Ento, kabedo moko nuti mi medo aloka loka i nwangu two con. I lembe manyen maeni, gi ketho wigi ikum formate, piny ma nyayu remo, ni neno ka etiyo maber calu biomarker.
Wel dhanu 574 ugam ucidho i somo ne, man ju m'ubedo i ie ne gibedo dhanu ma kumgi yot man gibedo ku rwom matung tung mi dongo pa two, nicaku i rwinyo pa wic nitundu i two ma jik. Ju ma timo sayusac gi ngiyo lac man rimo pa ju m'utimo sayusac man gitimo sayusac ikum paru migi.
Somu ne unwangu niya kadhiri pa formic acid i lac ubedo malu akeca ikind ju ma twoyo pa Alzheimer man urombo ku rwinyo pa wic ka juporo ku ju ma kum gi yot, ikinde ju ma rwinyo wic migi con. Eni nyutho nia formic acid copo bedu ni lanyuth ma pire tek pi acaki pa two Alzheimer.
Ber pa lembe, kinde ma ju ma timo sayusac gi ngiyo kadhiri pa formate i lac ku Alzheimer's blood biomarkers, ginwangu niya gicopo tito maber rwom pa two ma jaratwo ubekadhu kud i iye. Ento, lembe mukende mitere pi nyang ikum dul pa two Alzheimer ku formic acid.
"Urine formic acid unyutho bedo maber akeca pi nyang ikum two Alzheimer," ju goro gi uwacu. “Testing biomarker mi lac pi two Alzheimer utiye yot man ber man umitu juketh i pimo yot kum pa judongo.”
Wang, Y. et al. (2022) Neno lembe ikum acid mi lac calu lanyuth manyen pa two Alzheimer. Frontiers in neurobiology mi dongo. doi.org/10.3389/fnagi.2022.1046066.
Tags: dongo, two pa Alzheimer, lanyuth pa kwo, rimo, wic, two ma rii, two ma rii, jamb kum, wic, yath, daktari, formaldehyde, neurology, positron emission tomography, sayusac, tomography, urinalysis
I Pittcon 2023 i Philadelphia, Pennsylvania, wapenjo Japonji Joseph Wang, jatel wi Ralph N. Adams Prize mi oro maeni i Analytical Chemistry, ikum tic ma tung tung pa diro mi biosensor.
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